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. 2023 Feb 6;10(1):e001035. doi: 10.1136/bmjgast-2022-001035

Table 1.

Baseline demographics of all admission with AP by quintile

Q1 Q2 Q3 Q4 Q5 P value
No 156 94 60 48 38 <0.001*
Age, mean (SD) 52.4 (15.5) 59.8 (15.) 58.8 (14.4) 59.5 (12.8) 65.2 (13.7) <0.001*
Gender (male %) 97 (62%) 58 (62%) 42 (70%) 27 (56%( 19 (50%) 0.341
Medical history
 Type 2 diabetes mellitus 31 (19.9%) 17 (18.1%) 13 (21.7%) 5 (10.4%) 7 (18.4%) 0.578
 Past alcohol dependence 31 (19.9%) 17 (18.1%) 13 (21.7%) 5 (10.4%) 7 (18.4%) 0.058
 Ischaemic heart disease 148 (94.9%) 76 (80.9%) 55 (91.7%) 47 (97.9%) 35 (92.1%) <0.001*
 Hypertension 47 (30.1%) 30 (31.9%) 20 (33.3%) 14 (29.2%) 16 (42.1%) 0.627
 Chronic kidney disease 8 (5.13%) 9 (9.57%) 2 (3.33%) 2 (4.17%) 1 (2.63%) 0.375
 Chronic obstructive pulmonary disease 14 (8.97%) 8 (8.51%) 2 (3.33%) 1 (2.08%) 1 (2.63%) 0.228
 Cerebrovascular disease 4 (2.56%) 2 (2.13%) 4 (6.67%) 1 (2.08%) 2 (5.26%) 0.484
 Smoker 61 (39.1%) 23 (24.5%) 12 (20%) 12 (25%) 9 (23.7%) 0.044*
 Alcohol aetiology 99 (63.5%) 54 (57.4%) 28 (46.7%) 31 (64.6%) 19 (50%) 0.119
 Gallstone aetiology 51 (32.7%) 36 (38.3%) 22 (36.7%) 22 (45.8%) 18 (47.4%) 0.334
Premorbid ECOG
 1 35 (22.4%) 29 (30.9%) 16 (26.7%) 15 (31.3%) 13 (34.2%) 0.75
 2 14 (8.97%) 9 (9.57%) 6 (10%) 2 (4.17%) 2 (5.26%)
 3 13 (8.33%) 4 (4.26%) 7 (11.7%) 3 (6.25%) 3 (7.89%)
 4 3 (1.92%) 1 (1.06%) 0 (0%) 0 (0%) 1 (2.63%)
 Charlson Comorbidity Index 2 (0–3) 2 (1-4) 2 (1-3) 2 (1-3) 3 (1.75–4) 0.018
 Predicted 10-year survival 90% (77%–98%) 90% (53%–96%) 90% (77%–98%) 90% (77%–98%) 77% (53%–91.5%) 0.018
 Medical history of acute pancreatitis 61 (39.1%) 30 (31.9%) 18 (30%) 15 (31.3%) 8 (21.1%) 0.313
Laboratory results
 Amylase Median (IQR) 451 (140–1419) 702 (139–1872) 939 (165–2054) 864 (288–1891) 1248 (86–1931) 0.487
 C reactive protein Median (IQR) 54 (6.5–190) 32.1 (6.2–204) 16.9 (5.0–158.3) 14 (5.0–164.5) 79.5 (8.0–185) 0.914
 Albumin Mean (SD) 37.0 (8.1) 37.4 (7.2) 38.8 (8.4) 38.5 (7.1) 37.6 (8.9) 0.585
 Total protein Mean (SD) 68.2 (10.6) 69.1 (7.5) 70.8 (7.2) 69.1 (7.8) 65.8 (8.2) 0.152
 Alanine aminotransferase Median (IQR) 38.5 (18-96) 51 (20–163.5) 72 (30–208) 105.0 (29-265) 106.0 (31.0–187) 0.345
 Alkaline phosphatase Median (IQR) 127(88-177) 119.5 (84.5–171.5) 120.0 (92.0–210) 101 (84–150.5 122 (90–212) 0.583
 Platelets 290(210-387) 286(232-376) 262(218-338) 268(223-304) 302(198-386) 0.660
 Prothrombin time 15.2 (3.3) 164 (6.7) 16.0 (5.4) 14.7 (3.2) 15.2 (2.3) 0.245

*Statistically significant at<0.05 level

ECOG, Eastern Cooperative Oncology Group