Table 1.

Summary of Morphology Studies Measured at Larval Stage (96 hpf)

Endpoint		0 μM DMF		5 μM DMF		7 μM DMF		10 μM DMF
		WT	Nrf2a m/m	WT	Nrf2a m/m	WT	Nrf2a m/m	WT	Nrf2a m/m
% With edema	Pharyngula	20	18	29	35	44	41	21	20
	Hatching	7	18	0	38	12	38	6	53 *
	Protruding-Mouth	0	12	0	10	0	11	0	25
% With uninflated Swim Bladder	Pharyngula	58	63	75	64	61	58	50	62
	Hatching	21	31	6	20	6	38	20	38
	Protruding-Mouth	31	37	40	37	23	50	22	25
Length		-	-	-	Hatching: ↓ vs 5 μM DMF WT	-	Hatching: ↓ vs 7 μM DMF WT	-	Hatching: ↓ vs 10 μM DMF WT
Yolk Sac Area		-	-	-	-	-	-	-	Pharyngula & Protruding-mouth: ↑ vs 10 μM DMF WT
Pericardial Area		-	-	-	Pharyngula & Hatching: ↑ vs 0 μM DMF (WT and m/m) & 5 μM DMF WT	-	Pharyngula & Hatching: ↑ vs 0 μM DMF (WT and m/m) & 7 μM DMF WT	-	-
Islet Area		-	-					Hatching: Non-significant ↑ vs 0 μM DMF WT

^*X² (7, N = 118) = 2.64, P < 0.05, with Bonferroni correction