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Fig. 1. Schematic illustration of the Ir(iii) photosensitizer for two-photon photodynamic immunotherapy against melanoma. (a) Schematic illustration of the structures and properties of Ir-Bpa and Ir-pbt-Bpa. (b) Mechanism of action of Ir-pbt-Bpa as a photosensitizer for two-photon photodynamic immunotherapy in melanoma cancer cells.