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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Alcohol Clin Exp Res. 2022 Jul 18;46(8):1616–1629. doi: 10.1111/acer.14901

Figure 2:

Figure 2:

Alcohol withdrawal drives basal alterations to home-cage and open field behaviors in males and females while restraint stress drives alterations to behavior regardless of alcohol history. (A) Experimental design. (B) Alcohol intake in male and female mice. In No-stress mice, Home Cage (HC) test: (C) Seconds spent digging, (D) seconds spent rearing, (E) seconds spent grooming. In No-stress mice, Open Field (OF) test: (F) Seconds spent in the center and (G) number of center entries. In Stress mice, HC test: (H) Seconds spent digging, (I) seconds spent rearing, (J) seconds spent grooming. In Stress mice, OF test: (K) Seconds spent in the center and (L) number of center entries. @ = Main effect of Alcohol. ^ = Main effect of Sex. & = Interaction. Šídák Post hoc tests: * p<.05.