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. Author manuscript; available in PMC: 2023 Feb 8.
Published in final edited form as: Anal Chem. 2021 Mar 16;93(12):5028–5036. doi: 10.1021/acs.analchem.0c03693

Figure 2.

Figure 2.

metabCombiner RT mapping procedure. In (A), RT ordered pairs are selected from shared abundant (or identified) features, generating two lists that are subsequently intersected to obtain a final set of anchors. Features within a close retention time window of anchors are excluded. In (B), multiple GAM fits determine outlier anchors before the best k parameter value is chosen through 10-fold CV, which generates the final mapping.