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. 2022 Dec 15;119(51):e2212340119. doi: 10.1073/pnas.2212340119

Fig. 4.

Fig. 4.

S. aureus aminoglycoside tolerance in intact and mixed wounds. Percent survival of S. aureus to gentamicin (A) or tobramycin (B) in intact (structured) or mixed (homogenized) wounds compared to nonantibiotic treated portions of the same wound. Monoinfection is shown with open circles, coinfection with WT P. aeruginosa PA14 with closed circles, and coinfection with P. aeruginosa ΔpqsL with red circles. All P-values were determined by a Mann–Whitney test; asterisks indicate P < 0.01 comparing intact and mixed wounds. The following number of animals were used: Panel A: S. aureus monoinfection, n = 4; S. aureus/P. aeruginosa PA14 WT coinfection, n = 4; S. aureus/P. aeruginosa PA14 ΔpqsL coinfection, n = 4. Panel B: S. aureus monoinfection, n = 6; S. aureus/P. aeruginosa PA14 WT coinfection, n = 6; S. aureus/P. aeruginosa ΔpqsL coinfection, n = 5.