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. 2022 Dec 13;119(51):e2214285119. doi: 10.1073/pnas.2214285119

Fig. 4.

Fig. 4.

Replay enhanced differentiation of activity in the hippocampus. (A) Each fMRI trial consisted of three phases. 1) Watch cue (8 s): view a HippoCamera audio–video cue, 2) mentally relive (8 s; Exp. 2): engage in elaborative recall of the event, and 3) episodic probe (4 s): judge whether a probe word captured an aspect of the event. (B) For each phase, we quantified differentiation (1 – Pearson’s r) between mean activity patterns obtained for all pairs of replayed memories and between all pairs of baseline memories. (C) Differentiation scores for each task phase of the fMRI task. Circle markers and solid lines depict data from experiment 1, whereas triangle markers and dashed lines depict data from experiment 2. Open triangles reflect experiment 2 participants who failed the Montreal Cognitive Assessment. * = P < 0.05, *** = P < 0.001.