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. Author manuscript; available in PMC: 2023 Feb 8.
Published in final edited form as: Exp Gerontol. 2022 Jul 30;167:111904. doi: 10.1016/j.exger.2022.111904

Figure 3. Age-related changes in CD4+ T cell compartment in BALF following tuberculin challenge.

Figure 3.

(A) Number of CD4+ T cells in BALF of adult and aged macaques prior to tuberculin lung instillation (Week 8). Number of CD4+ effector memory T cells (B), CD4+ central memory T cells (C), and CD69+CD4+ T cells (D) in BALF of adult and aged macaques prior to tuberculin lung instillation (Week 8). (E) Number of CD4+ T cells in BALF of adult and aged macaques 48 hours post-tuberculin challenge. Number of CD4+ effector memory T cells (F), CD4+ central memory T cells (G), and CD69+CD4+ T cells (H) in BALF of adult and aged macaques 48 hours post-tuberculin challenge. (I) Number of CD4+ T cells in BALF of adult and aged macaques 72 hours post-tuberculin challenge. Number of CD4+ effector memory T cells (J), CD4+ central memory T cells (K), and CD69+CD4+ T cells (L) in BALF of adult and aged macaques 72 hours post-tuberculin challenge. One-way ANOVA post-Tukey analyses comparing means between groups as indicated; *p<0.05. TST = tuberculin instillation; NaCl = saline (control) instillation.