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. Author manuscript; available in PMC: 2023 Feb 8.
Published in final edited form as: Exp Gerontol. 2022 Jul 30;167:111904. doi: 10.1016/j.exger.2022.111904

Figure 4. Adult macaques have increased T cells present in BALF maintained over time following tuberculin instillation.

Figure 4.

(A) Proportions of T cells (CD45+CD3+) in BALF of adult and aged macaques prior to tuberculin lung instillation (Week 16). (B) Proportions of T cells (CD45+CD3+) in BALF of adult and aged macaques 48 hours post-tuberculin challenge. Number of CD8+ T cells (C), CD8+ effector memory T cells (D), CD8+ central memory T cells (E), and CD69+CD8+ T cells (F) in BALF of adult and aged macaques 48 hours post-tuberculin challenge. (G) Proportions of T cells (CD45+CD3+) in BALF of adult and aged macaques 72 hours post-tuberculin challenge. Number of CD8+ T cells (H), CD8+ effector memory T cells (I), CD8+ central memory T cells (J), and CD69+CD8+ T cells (K) in BALF of adult and aged macaques 72 hours post-tuberculin challenge. One-way ANOVA post-Tukey analyses comparing means between groups as indicated; *p<0.05, **p<0.01. TST = tuberculin instillation; NaCl = saline (control) instillation.