Table 1. Quality-of-Life Trajectories.

Source	No. of patients	Follow-up, moa	Change in status
			Overall QOL	Physical well-being	Mental well-being	Symptom burden	Self-rated health
Brown et al,11 2015	122b	10c	NR	SF-36 physical health worse	SF-36 mental health better	MSAS worse, POS-S worse	NR
Da Silva-Gane et al,18 2012	30	15	NR	SF-36 physical health no change	SF-36 mental health better	SWLS no change, HADS depression no change, HADS anxiety no change	NR
Kilshaw et al,25 2016	41	11c	EQ5D worse	NR	NR	TUG worse, Barthel Index no change	NR
Murtagh et al,33 2011	49	8	NR	NR	NR	MSAS worse, POS-S worse	NR
Phair et al,34 2018	42	12	EQ5D worse	NR	NR	NR	NR
Rubio Rubio et al,40 2019	64	NR	NR	SF-36 physical health no change	SF-36 mental health better	NR	NR
Seow et al,41 2013	63	24	NR	KDQOL-SF physical health worse	KDQOL-SF mental health better	NR	NR
van Loon et al,46 2019	89	NR	EQ5D worse	NR	NR	NR	VAS worse

Abbreviations: EQ5D, EuroQol-5D Scale; HADS, Hospital Anxiety and Depression Scale; KDQOL-SF, Kidney Disease Quality of Life Short Form; MSAS, Memorial Symptom Assessment Scale; NR, not reported; POS-S, Palliative Care Outcome Scale–Symptoms; QOL, quality of life; SF-36, 36-Item Short Form Health Survey; SWLS, Satisfaction With Life Scale; TUG, Timed Up-and-Go; VAS, visual analog scale.

^a Unless otherwise indicated, data are expressed as mean.

^b Response rates for each survey ranged from 55% to 74%.

^c Indicates median values.