Table 2.
Simple and Multivariable Logistic Regression Analysis of Covariates Association With Mortality
| Variable | Crude | Adjusteda | ||
|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Age | … | <.001 | … | <.001 |
| ȃ<6 mo | 3.54 (2.81–4.50) | 2.07 (1.59, 2.73) | … | |
| ȃ6 mo–1 y | 2.50 (2.01–3.15) | 1.52 (1.19–1.98) | … | |
| ȃ1–2 y | 1.95 (1.55, 2.49) | 1.38 (1.06–1.81) | … | |
| ȃ2–5 y | Ref | Ref | … | |
| Sex | … | .005 | … | .01 |
| ȃMale | Ref | Ref | … | |
| ȃFemale | 1.18 (1.05–1.32) | 1.18 (1.04–1.34) | … | |
| WHO region | … | <.001 | … | <.001 |
| ȃEuropean Region | Ref | Ref | … | |
| ȃAfrican Region | 62.05 (38.70–108.26) | 130.62 (55.75–422.73) | … | |
| ȃRegion of the Americas | 42.65 (25.91–75.82) | 91.03 (38.31–296.76) | … | |
| Eastern Mediterranean Region | 15.20 (9.24–26.84) | 39.44 (16.54–128.84) | … | |
| ȃSouth East Asia Region | 5.62 (2.14–13.33) | 31.33 (9.24–120.01) | … | |
| ȃWestern Pacific Region | 8.75 (5.21–15.76) | 24.12 (9.44–81.62) | … | |
| Acute vs persistent | … | <.001 | … | .03 |
| ȃPersistent (≥14 d) | 3.46 (2.31–4.94) | 1.91 (1.01–3.25) | … | |
| ȃAcute (<14 d) | Ref | Ref | … | |
| Bloody vs watery | … | .24 | … | .95 |
| ȃWatery | Ref | Ref | … | |
| ȃBloody | .59 (.21–1.27) | .97 (.24–2.55) | … | |
| Vomiting | … | <.001 | … | .10 |
| ȃNot vomiting | 1.43 (1.26–1.62) | 1.13 (.98–1.30) | … | |
| ȃVomiting | Ref | Ref | … | |
| Dehydration typeb | … | <.001 | … | <.001 |
| ȃNone | Ref | Ref | … | |
| ȃSome | .71 (.56–.91) | .93 (.72–1.20) | … | |
| ȃSevere | 3.12 (2.50–3.96) | 3.79 (3.01–4.83) | … | |
| Rotavirus positivity (using ELISA) | … | <.001 | … | <.001 |
| ȃRotavirus positive | Ref | Ref | … | |
| ȃRotavirus negative | 2.20 (1.88–2.59) | 2.29 (1.92–2.74) | … | |
| Year | .90 (.88–.92) | .001 | .94 (.92–.96) | <.001 |
The adjusted model includes an interaction term between acute/persistent presentation and watery/bloody presentation.
Abbreviations: CI, confidence interval; ELISA, enzyme-linked immunosorbent assay; OR, odds ratio.
Adjusted for all variables.
Dehydration severity is categorized based on WHO classification [13].