Figure 1.

Patient disposition. ^aThe most common reasons for screening failure were negative parasitology (746 patients, 22.6%), laboratory abnormalities (338 patients, 13%), age <4 years or >50 years (329 patients, 12.7%), severe malnourishment (230 patients, 8.9%), or other reasons (245 patients, 9.4%). One patient died during screening. ^bOne additional patient discontinued the study treatment due to AEs but did not receive rescue medication and completed the study. ^cThree patients missed the EOT (day 28) visit but were included at later visits. Abbreviations: AE, adverse event; D, day; EOT, end of treatment; MF, miltefosine; PM, paromomycin; SSG, sodium stibogluconate.