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. Author manuscript; available in PMC: 2023 Feb 8.
Published in final edited form as: Nat Genet. 2022 May;54(5):527–530. doi: 10.1038/s41588-022-01074-3

Table 2 |.

Cardiometabolic traits, diseases and related covariates in the CARDINAL study cohorts

Cardiometabolic endpoints and related traits Potential confounders and effect modifiers
Anthropometry Demography
Height and weight Age
Waist and hip circumference Gender
Biomarkers Ethnicity
Blood glucose, insulin and HbA1c Education
Creatinine (serum and urine) Marital Status
Lipids (TC/LDL/TG/HDL) Behaviors
Urinary protein and albumin Smoking
Platelets, red and white blood cell indices Alcohol
Liver function parameters Physical activity
Disease endpoints Diet
Hypertension Health history
Dyslipidemia Medical history
Diabetes Family health history
Stroke
Kidney disease

Liver function parameters: are alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and gamma glutamyl transferase. HbA1c, glycated hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TC, total cholesterol; TG, triglycerides.