Table 2.
CLDN18.2 | |||||||||
---|---|---|---|---|---|---|---|---|---|
Score 0 | Score 1 | Score 2 | Score 3 | P value | |||||
n | % | n | % | n | % | n | % | ||
Age | |||||||||
<60 | 7 | 43.8 | 4 | 25 | 3 | 18.8 | 2 | 12.5 | .479 |
≥60 | 24 | 46.2 | 17 | 32.7 | 8 | 15.4 | 3 | 5.8 | |
Gender | |||||||||
Male | 20 | 64.5 | 18 | 85.7 | 9 | 81.8 | 4 | 80 | .185 |
Female | 11 | 35.5 | 3 | 14.3 | 2 | 18.2 | 1 | 20 | |
Grade | |||||||||
G1 | 16 | 51.6 | 9 | 42.9 | 4 | 36.4 | 2 | 40 | .633 |
G2 | 12 | 38.7 | 10 | 47.6 | 6 | 54.5 | 3 | 60 | |
G3 | 3 | 9.7 | 2 | 9.5 | 1 | 9.1 | 0 | 0 | |
Localization | |||||||||
Head | 21 | 67.7 | 16 | 76.2 | 9 | 81.8 | 5 | 100 | .067 |
Body | 5 | 16.1 | 3 | 14.3 | 2 | 18.2 | 0 | 0 | |
Tail | 5 | 16.1 | 2 | 9.5 | 0 | 0 | 0 | 0 | |
Tumor stage | |||||||||
1B | 8 | 25.8 | 3 | 14.3 | 4 | 36.4 | 2 | 40 | .731 |
1C | 4 | 12.9 | 0 | 0 | 1 | 9.1 | 0 | 0 | |
2 | 9 | 29 | 9 | 42.9 | 4 | 36.4 | 2 | 40 | |
3 | 10 | 32.3 | 9 | 42.9 | 2 | 18.2 | 1 | 20 | |
Node stage | |||||||||
0 | 13 | 41.9 | 9 | 42.9 | 5 | 45.5 | 0 | 0 | .579 |
1 | 10 | 32.3 | 7 | 33.3 | 5 | 45.5 | 3 | 60 | |
2 | 8 | 25.8 | 5 | 23.8 | 1 | 9.1 | 2 | 40 | |
Clinical stage | |||||||||
IA | 6 | 19.4 | 3 | 14.3 | 4 | 36.4 | 0 | 0 | .645 |
IB | 4 | 12.9 | 4 | 19 | 1 | 9.1 | 0 | 0 | |
IIA | 3 | 9.7 | 2 | 9.5 | 0 | 0 | 0 | 0 | |
IIB | 10 | 32.3 | 7 | 33.3 | 5 | 45.5 | 3 | 60 | |
III | 8 | 25.8 | 5 | 23.8 | 1 | 9.1 | 2 | 40 | |
PNI | |||||||||
Yes | 24 | 77.4 | 13 | 61.9 | 8 | 72.7 | 3 | 60 | .41 |
No | 7 | 22.6 | 8 | 38.1 | 3 | 27.3 | 2 | 40 | |
LVI | |||||||||
Yes | 17 | 54.8 | 12 | 57.1 | 6 | 54.5 | 4 | 80 | .48 |
No | 14 | 45.2 | 9 | 42.9 | 5 | 45.5 | 1 | 20 | |
Necrosis | |||||||||
Yes | 4 | 12.9 | 3 | 18.2 | 2 | 18.2 | 0 | 0 | .799 |
No | 27 | 87.1 | 18 | 81.8 | 9 | 81.8 | 5 | 100 | |
Exitus | |||||||||
Yes | 24 | 82.8 | 17 | 81 | 8 | 80 | 3 | 60 | .361 |
No | 5 | 17.2 | 4 | 19 | 2 | 20 | 2 | 40 |
CLDN18.2 = claudin 18.2, LVI = lymphovascular invasion, PDAC = pancreatic ductal adenocarcinoma, PNI = perineural invasion.