Table 1. Hydrodynamic diameter, ζ potential, and PNA loading in NPs.
The data are shown as means ± SD (n = 3). Scr-sγPNA/NNP was the physical mixture of Scr-sγPNA-21–loaded NNP and Scr-sγPNA-10b–loaded NNP, sγPNA/BNP was the mixture of sγPNA-21–loaded BNP and sγPNA-10b–loaded BNP, and PNA/BNP was the mixture of PNA-21–loaded BNP and PNA-10b–loaded BNP. NNP indicates PLA-HPG NP, and BNP indicates PLA-HPG-CHO NP.
| Formulation | Hydrodynamic diameter (nm) | ζ potential (mV) | PNA loading (nmol/mg) |
|---|---|---|---|
| sγPNA-21/NNP | 160 ± 4 | −21 ± 3 | 1.5 ± 0.2 |
| sγPNA-21/BNP | 170 ± 4 | −30 ± 4 | 1.5 ± 0.4 |
| sγPNA-10b/NNP | 150 ± 6 | −21 ± 5 | 1.6 ± 0.3 |
| sγPNA-10b/BNP | 160 ± 5 | −32 ± 3 | 1.4 ± 0.3 |
| Scr-sγPNA/NNP | 180 ± 6 | −22 ± 2 | 1.4 ± 0.2 |
| sγPNA/BNP | 170 ± 3 | −32 ± 3 | 1.5 ± 0.3 |
| PNA/BNP | 170 ± 6 | −28 ± 2 | 1.9 ± 0.2 |