Figure 2.

Non-linear MR analysis of serum 25(OH)D with CRP concentration. The dot represents the reference point of serum 25(OH)D of 50 nmol/L. The shaded areas represent the 95% confidence intervals. Adjustment includes age, sex, assessment centre, birth location, SNP array, top 40 genetic principal components and nuisance factors that could affect serum 25(OH)D and/or CRP measurement, including month in which blood sample was taken, fasting time before blood sample was taken and sample aliquots for measurement. CRP, C-reactive protein; 25(OH)D, 25-hydroxyvitamin D.