Anjum 2017.
Study characteristics | |
Methods |
Study design: parallel‐group randomised trials Duration of trial: July 2014 to January 2016 Duration of follow‐up: "All outcomes were evaluated daily during the hospital stay, and postoperative follow‐up was conducted on postoperative days 30 and 90" Country of origin: China |
Participants |
Baseline characteristics
Number randomised: 190 participants
Number analysed: 184 participants
Intervention: MBP+oAB
Control: MBP
Inclusion criteria 18 years of age or older and scheduled for elective colorectal surgery Exclusion criteria Patients were excluded if they had any preoperative infection or bowel obstruction, if they were undergoing emergency laparotomy, if they used antibiotics 2 weeks preoperatively, or were being treated with steroids or immunosuppressants preoperatively Baseline imbalances None |
Interventions |
Comparison
MBP
oAB
Perioperative intravenous antibiotic prophylaxis
Adherence to regimen: Two patients were excluded due protocol violations |
Outcomes |
Outcomes sought in review and reported in trial
Outcomes sought but not reported in trial
Outcomes reported in trial but not used in review
|
Notes |
Source of funding: This work was supported by the National Natural Science Foundation of China (grant number 81270478) Conflicts of interest: ‐ Ethics approval: The study was approved by the ethical committee of the Jinling Hospital Informed consent: All participants gave their informed consent before randomisation Clinical trials registration: ‐ Sample size calculation: "To reach a power of 80%, it was estimated that 90 patients would be required in each group to detect the difference of SSI between 18% and 6% with a type I error of 0.05. A total sample size of 95 patients was established for each arm." |