Horie 2007.

Study characteristics
Methods	Study design: Parallel‐group randomised trials Duration of trial: April 2002 to December 2006 Duration of follow‐up: ‐ Country of origin: Japan
Participants	Baseline characteristics Number randomised: 91 participants Number analysed: 91 participants Intervention: MBP+oAB Number of participants [n]: 46 Age [years; mean (range)]: 69 (16‐85) Gender [male/female; n]: 25/21 Control: MBP Number of participants [n]: 45 Age [years, mean (range)]: 64.7 (39‐86) Gender [male/female; n]: 29/16 Inclusion criteria  Elective surgery for colorectal cancer Exclusion criteria Quote: "Any patient with a colonic obstriction, experience of abdominal operation and resection of other organs synchronously were excluded" Baseline imbalances none
Interventions	Comparison Intervention: MBP+oAB Control: MBP MBP Agent(s): polyethylene glycol lavage solution Dose per administration: 2000 mL Time(s) of intake: 16 hours before surgery Route: oral Concomitant medications: ‐ oAB Agent(s): kanamycin Dose per administration: 1500 mg/day Time(s) of intake: daily for 3 consecutive days before operation Route:oral Concomitant medications: ‐ Perioperative intravenous antibiotic prophylaxis Agent(s): cefotiam Dose per administration: 1 g Time(s) of intake: Quote: ""after induction of anaesthesia and again two times a day for 3 consecutive days after operation" Adherence to regimen: ‐
Outcomes	Outcomes sought in review and reported in trial SSI Anastomotic leakage Outcomes sought but not reported in trial Mortality Postoperative complications (mild D/C I + II or severe D/C III+IV) Incidence of postoperative ileus Length of hospital stay Side effects of Intervention(s) Outcomes reported in trial but not used in review Bacteria cultured from preoperative stool, intraoperative mucosal swabs and from the peritoneal fluid
Notes	Source of funding: ‐ Conflicts of interest: ‐ Ethics approval: ‐ Informed consent: "Informed consent was obtained from all patients" Clinical trials registration: ‐ Sample size calculation: ‐