| Koskenvuo 2019 |
Low risk of bias |
Generation of randomisation sequence and concealment of allocation were adequate. There was no baseline imbalance that would suggest a problem with randomisation. |
Low risk of bias |
Both participants and those delivering the intervention were aware of intervention received. There were no deviations from intervention. |
Low risk of bias |
95% of randomised patients were analysed in the modified intention‐to‐treat analysis. |
Low risk of bias |
The raters were blinded, but even without blinding it is unlikely that knowledge of the intervention would have influenced the rating, as the diagnosis is made using well‐defined criteria. |
Low risk of bias |
The trial was registered with ClinicalTrials.gov (NCT02652637) and EudraCT (2015‐004559‐38). |
Low risk of bias |
Low risk of bias in all domains. |
