Table 7.
Multivariate regression model for all-cause mortality
| Variable | Hazard ratio | 95% CI | p-value |
|---|---|---|---|
|
| |||
| Sodium (per 1 mEq/L) | 0.89 | 0.82–0.96 | 0.004 |
| B-type natriuretic peptide (per 100 pg/mL) | 1.08 | 1.02–1.14 | 0.009 |
| Age at implant (per year) | 1.04 | 1.00–1.08 | 0.03 |
| Gender male | 1.45 | 0.49–4.32 | 0.50 |
| LVAD indication (bridge-to-transplant) | 0.71 | 0.31–1.62 | 0.41 |
| Loop diuretic use | 0.62 | 0.31–1.23 | 0.17 |
| Preoperative body-mass index | 0.97 | 0.91–1.02 | 0.23 |
| Diabetes mellitus | 0.89 | 049–1.63 | 0.71 |
| Chronic obstructive lung disease | 0.64 | 0.31–1.33 | 0.23 |
| Peripheral vascular disease | 3.50 | 1.46–8.38 | 0.005 |
| Estimated GFR | 1.01 | 0.99–1.02 | 0.44 |
Multivariate Cox regression model adjusting for covariates shown demonstrated lower serum sodium was significantly associated with all-cause mortality.
GFR, glomerular filtration rate; LVAD, left ventricular assist device.