Author response table 2. Observed frequencies of spurious detection of discordant evolution for different types of site pairs, compared to the expected.

Multinomial test p-value = 0.0018.

site types	#FP	#total possible FP	expected FP frequency	observed FP frequency
(pos,pos)	0	190	0,0385	0
(pos,neg)	7	400	0,0810	0,1556
(neg,neg)	4	180	0,0364	0,0889
(pos,neu)	5	1200	0,2429	0,1111
(neg,neu)	19	1200	0,2429	0,4222
(neu,neu)	10	1770	0,3583	0,2222