Table 2.
Comparison of relative gene expression profiles among study groups.
| Variables | Formaldehydea | Formaldehyde + curcuminb | Shamc | Controld | P value |
|---|---|---|---|---|---|
| FSHR | 1.29 ± 0.45 | 1.14 ± 0.31 | 1.28 ± 0.81 | 1.02 ± 0.15 | 0.64 |
|
| |||||
| GDF-9 | 1.3 ± 0.42 | 1.03 ± 0.14 | 0.99 ± 0.5 | 1.01 ± 0.52 | 0.84 |
|
| |||||
| KL | 3.05 ± 0.75 | 2.4 ± 0.85 | 0.87 ± 0.22 | 0.81 ± 0.33 | 0.06 0.6a,b 0.03a,c 0.03a,d 0.19b,c 0.34b,d 0.9c,d |
|
| |||||
| FIGLA | 0.91 ± 0.36 | 1.44 ± 0.45 | 3.07 ± 0.34 | 3.59 ± 0.55 |
0.006
0.44a,b 0.009a,c 0.02a,d 0.02b,c 0.01b,d 0.99c,d |
|
| |||||
| BAX | 1.18 ± 0.35 | 1.15 ± 0.24 | 0.74 ± 0.11 | 1.1 ± 0.33 | 0.58 |
|
| |||||
| BCL-2 | 0.99 ± 0.26 | 1.01 ± 0.2 | 2.94 ± 0.74 | 2.94 ± 0.42 |
0.007
0.91a,b 0.03a,c 0.02a,d 0.01b,c 0.09b,d 0.73c,d |
|
| |||||
| BAX/BCL-2 | 1.14 | 1.03 | 1.11 | 1.00 | — |
FSHR: follicle-stimulating hormone receptor, GDF-9: growth differentiation factor-9, FIGLA: factor in germ line alpha, Kl: klotho, BCL-2: B-cell lymphoma 2, and BAX: BCL-2-like protein 4. The data were shown as the mean ± SEM. The Mann–Whitney and Kruskal–Wallis tests were carried out, respectively, to compare two and all groups. SEM: standard error of mean. P < 0.05 was considered as bold values.