Fig. 4. Alterations in fecal, urine and plasma metabolites.
A Volcano plot showing fecal lipid metabolites statistically significantly altered by dietary intervention (A) and in control group (B). B Changes in urinary metabolites after dietary intervention. Only metabolites that changed statistically significantly are shown. V2 refers to pre-intervention levels, V3 to post-intervention; n (CONT V2) = 21; n (CONT V3) = 21; n (DIET V2) = 24; n (DIET V3) = 24). C Changes in plasma metabolites after dietary intervention. 5-hydroxyindole-3-acetic acid and 3-hydroxykynurenine statistically significantly decreased in the diet group; V2 refers to pre-intervention levels, V3 to post-intervention; n (CONT V2) = 21; n (CONT V3) = 21; n (DIET V2) = 24; n (DIET V3) = 24).