Table 3.
Baseline scores of secondary efficacy variables
| Baseline | Variable | Active (n = 60) | Control (n = 35) | p-value | Difference between groups Mean (95% CI) |
|---|---|---|---|---|---|
| CGI-S | CGI severity of illness |
4.68 (0.75) 5 (3; 7) n = 60 |
4.60 (0.95) 5 (2; 6) n = 35 |
0.73 | 0.083 (− 0.273; 0.429) |
| BYI | Beck Youth Inventories | ||||
| Anxiety |
66.9 (26.5) 70.5 (3; 99.9) n = 60 |
64.9 (30.3) 74.1 (12; 99.6) n = 35 |
0.75 | 1.94 (− 9.98; 13.56) | |
| Depression |
72.1 (26.2) 79.6 (1.9; 99.8) n = 60 |
63.4 (31.8) 74.6 (1.9; 99.7) n = 35 |
0.16 | 8.77 (− 3.54; 20.69) | |
| Anger |
79.4 (25.5) 89.9 (4.2; 99.8) n = 60 |
71.6 (29.5) 84.3 (7.9; 99.4) n = 35 |
0.18 | 7.76 (− 4.07; 18.94) | |
| Disruptive behaviour |
76.0 (24.2) 82.1 (13.1; 99.1) n = 60 |
69.9 (27.6) 78.2 (13.1; 98.4) n = 35 |
0.26 | 6.14 (− 4.69; 16.83) | |
| Self-concept |
36.3 (27.6) 29.5 (1; 97.6) n = 60 |
40.2 (31.0) 26.8 (1.4; 93.9) n = 35 |
0.53 | − 3.88 (− 16.05; 8.51) | |
| SNAP-IV | ADHD |
33.7 (10.2) 34.5 (2; 53) n = 60 |
30.2 (11.2) 31 (1; 48) n = 35 |
0.12 | 3.56 (− 0.90; 8.00) |
| ODD |
16.3 (6.1) 16.5 (0; 28) n = 60 |
14.4 (6.7) 15 (3; 24) n = 35 |
0.15 | 1.95 (− 0.75; 4.55) | |
| ECBI | ECBI intensity scale |
149.5 (32.9) 146.5 (65; 209) n = 60 |
136.1 (28.1) 136 (66; 197) n = 35 |
0.049 | 13.5 (0.1; 26.6) |
| ECBI Problem scale |
19.2 (6.5) 19 (3; 31) n = 60 |
17.0 (6.5) 16 (5; 33) n = 35 |
0.12 | 2.22 (− 0.53; 4.95) | |
| FBIM | Family burden of illness |
14.1 (5.2) 14 (3; 24) n = 60 |
15.6 (5.5) 16 (4; 24) n = 35 |
0.19 | − 1.50 (− 3.72; 0.71) |
PR-ESSENCE vs Controls (FA set). Stochastic Imputation
For continuous variables Mean (SD)/Median (Min; Max) / n = is presented for comparison between groups the Fisher´s Non Parametric Permutation Test was used for continuous variables. The confidence interval for the mean difference between groups is based on Fishers non-parametric permutation test