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. 2022 Nov 14;30(1):17–27. doi: 10.1007/s40292-022-00551-4

Table 2.

Evidences concerning CACS estimation in hypertension

Study Conclusion References
INSIGHT CACS predicted cardiovascular events also in high-risk asymptomatic hypertensive patients [43]
INSIGHT In hypertensive patients, progression of CAC is associated with long-term cardiovascular events [44, 45]
INSIGHT Patients with hypertension and diabetes mellitus can be stratified into a lower cardiovascular risk in the absence of CAC. [46]
Heinz Nixdorf Recall Risk of myocardial infarction and stroke in hypertension but also in prehypertension depended on the degree of CAC [47]
INSIGHT Slower progression of coronary calcification in hypertensive patients on nifedipine once daily versus co-amilozide [48]
ACTION Nifedipine GITS was not effective in slowing down the progression of calcium in advanced atherosclerotic plaques in patients with stable angina pectoris, half of them hypertensives [49]

CACS coronary artery calcium score, CAC coronary artery calcium