Table 2.
LMM ESTIMATION ON PRIMARY AND SECONDARY OUTCOMES FOR VISIT 5 (PRIMARY ENDPOINT)
| A. VISIT 5 VS. VISIT 1 | |||||||
|---|---|---|---|---|---|---|---|
| DSMQ b (SE) |
HbA1c b (SE) |
Systolic BP b (SE) |
Diastolic BP b (SE) |
Memory b (SE) |
Attention/Executive b (SE) |
Prospective Memory b (SE) |
|
| GROUPS (AT VISIT 1) | −0.060 (0.346) |
0.178 (0.217) |
1.852 (2.583) |
1.181 (1.588) |
−0.019 (0.113) |
−0.035 (0.094) |
0.054 (0.177) |
| VISITS (ALL): 5 v. 1 |
0.944
***
(0.243) |
0.077 (0.179) |
−5.688* (2.273) |
−3.322* (1.362) |
0.311
**
(0.055) |
0.207
**
(0.046) |
0.676
**
(0.165) |
| GROUPS x 5 v. 1 | −0.160 (0.345) |
−0.122 (0.254) |
2.125 (3.209) |
2.918 (1.923) |
0.205
**
(0.078) |
−0.056 (0.065) |
−0.043 (0.236) |
| B. All VISITS UP TO VISIT 5 VS. VISIT 1 | |||||||
| GROUPS (AT VISIT 1) | −0.060 (0.347) |
0.179 (0.210) |
1.843 (2.547) |
1.177 (1.570) |
−0.019 (0.113) |
−0.035 (0.097) |
0.054 (0.173) |
| VISITS (All): 3 v. 1 |
0.773
***
(0.215) |
−0.032 (0.145) |
0.933 (1.959) |
0.563 (1.203) |
0.272** (0.051) |
0.124
**
(0.040) |
0.396
*
(0.155) |
| VISITS (All): 5 v. 1 |
1.040
***
(0.229) |
0.058 (0.152) |
−5.641** (2.070) |
−3.043* (1.271) |
0.316
**
(0.054) |
0.197
**
(0.043) |
0.683
**
(0.165) |
| GROUPS x 3 v. 1 | −0.162 (0.314) |
0.007 (0.210) |
−3.858 (2.822) |
−1.766 (1.733) |
0.077 (0.074) |
0.017 (0.058) |
0.012 (0.226) |
| GROUPS x 5 v. 1 | −0.291 (0.326) |
−0.091 (0.217) |
2.070 (2.928) |
2.569 (1.798) |
0.186
*
(0.076) |
−0.057 (0.061) |
−0.047 (0.237) |
DSMQ = Diabetes Self-Management Questionnaire; HbA1c = hemoglobin A1c; BP = blood pressure;
Visit indicators defined as visit 1 = 0 (reference), intervention group indicator defined as adaptive CCT = 1, active control CCT = 0 (reference)
Coefficient on group indicator estimates the difference in the outcome between adaptive CCT group compared to active control (reference) at visit 1. Coefficient on visit estimates the difference in the outcome between visit 5 compared to visit 1 in the active control group (reference). The main test of interest, intervention group X visit interaction, estimates whether the change from visit 1 in the outcome differed between adaptive CCT group compared to active control.
p<0.05;
p<0.01;
p<0.001