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. 2023 Feb 9;14(2):94. doi: 10.1038/s41419-023-05634-1

Fig. 2. The current model of pyroptosis primarily includes the classical, non-classical, caspase-3-dependent, and caspase-8-dependent pathways.

Fig. 2

In addition, granzyme B cleaves GSDME, granzyme A cleaves GSDMB, caspase-8 cleaves GSDMC, and SpeB cleaves GSDMA.