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Vascular smooth muscle cell (VSMC) exosome biogenesis and release. See text for interpretation. miR145, micro RNA 145; ER, endoplasmic reticulum; TNF-α, tumor necrosis factor alpha; MVB, multivesicular bodies; nSM2, neutral sphingomyelinase 2; SNARES (Soluble NSF Attachment protein Receptor Superfamily). Adapted from Dusso et al. (2018) with permission.
