Table 3.
Univariable and multivariable Cox regression analysis in PIMREG expression and clinical pathological characteristics of patients.
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |||
| Age N=539 |
<=60 | 269 | 1.765 (1.298-2.398) | <0.001 | 1.847 (1.195-2.853) | 0.006 |
| >60 | 270 | |||||
| Gender N=539 |
Female | 186 | 0.930 (0.682-1.268) | 0.648 | 0.996 (0.639-1.553) | 0.985 |
| Male | 353 | |||||
| T stage N=539 |
T1&T2 | 349 | 3.228 (2.382-4.374) | <0.001 | 1.427 (0.626-3.255) | 0.398 |
| T3&T4 | 190 | |||||
| N stage N=257 |
N0 | 241 | 3.453 (1.832-6.508) | <0.001 | 1.282 (0.630-2.610) | 0.493 |
| N1 | 16 | |||||
| M stage N=506 |
M0 | 428 | 4.389 (3.212-5.999) | <0.001 | 2.627 (1.557-4.432) | <0.001 |
| M1 | 78 | |||||
| Pathologic stage N=536 |
Stage I &Stage II |
331 | 3.946 (2.872-5.423) | <0.001 | 1.227 (0.484-3.111) | 0.667 |
| Stage III &Stage IV |
205 | |||||
| Histologic grade N=531 |
G1&G2 | 249 | 2.702 (1.918-3.807) | <0.001 | 1.441 (0.860-2.413) | 0.165 |
| G3&G4 | 282 | |||||
| PIMREG | 539 | 2.796 (2.197-3.557) | <0.001 | 2.014 (1.364-2.974) | <0.001 | |
Bold font is used to indicate that the difference is statistically significant.