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LIMT over-expression could suppress tumor growth in vivo (A,B) Growth curves of xenograft tumors and the tumor size treated with control, sorafenib, LIMT plasmid, or sorafenib plus LIMT plasmid (n = 3 per group). (C) TUNEL was used to analyze cell apoptosis in the treatment groups. (D) RT-qPCR was used to analyze the mRNA expression levels of E-cadherin, Vimentin and FN-1.
