Table1 The siRNA sequences used in this study

Name	Sequence
LIMT-homo-177	Sense: 5′-CCAUUCAUGUCAGCAGUUATT-3′; Antisense: 5′-UAACUGCUGACAUGAAUGGTT-3′
LIMT-homo-295	Sense: 5′-GCAGAACGUGAGGGUGUAATT-3′ Antisense: 5′-UUACACCCUCACGUUCUGCTT-3′
LIMT-homo-888	Sense: 5′-GCUUCCAACCUCCAUUGCATT-3′; Antisense: 5′-UGCAAUGGAGGUUGGAAGCTT-3′
miR-665 mimic	Sense: 5′-ACCAGGAGGCUGAGGCCCCU-3′; Antisense: 5′-GGGCCUCAGCCUCCUGGUUU-3′
miR-665 inhibitor	5′-AGGGGCCUCAGCCUCCUGGU-3′;