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. 2023 Feb 9;13(8):5058–5069. doi: 10.1039/d2ra08221g

The greenness profile of the proposed NADES-DLLME method as determined by using the eco-scale tool.

Items Penalty points (PPs)
1. Reagents
1.1. Ethanol Amount <10 mL 1
Hazard type Single word: danger 2
Hazard amount 2 Pictograms 2
Total PPs = 4
1.2. Menthol Amount <10 mL 1
Hazard type Single word: warning 1
Hazard amount 1 Pictogram 1
Total PPs = 1
1.3. Acetic acid Amount <10 mL 1
Hazard type Single word: danger 2
Hazard amount 2 Pictogram 2
Total PPs = 4
1.4. NaCl Amount 0.4 g 0
Hazard type 0 0
Hazard amount 0 0
Total PPs = 0
2. Instruments
2.1. Energy (kW h per sample) LC-UV ≤ 0.1 0
2.2. Occupational hazard No hermetic sealing release of gas or vapor into air 0
Total PPs = 0
3. Waste
3.1. Waste amount 1–10 mL 3
3.2. Waste treatment No treatment 3
Total PPs = 6
Total penalty points 15
Eco-scale score 100 − 15 = 85