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. 2023 Jan 26;14:1028431. doi: 10.3389/fneur.2023.1028431

Table 4.

Factors related to recurrent ischemic stroke in males and females.

Univariate analysis Multivariate analysis
Crude OR (95% CI) P-value Adjust OR (95% CI) P-value
Male patients
HTN 4.63 (3.42–6.27) <0.001 4.86 (3.34–7.08) <0.001
DM 1.75 (1.34–2.28) <0.001 1.11 (0.79–1.56) 0.552
Alcohol drinking 3.62 (2.77–4.74) <0.001 2.41 (1.73–3.34) <0.001
Smoking 5.59 (4.22–7.39) <0.001 5.11 (3.65–7.16) <0.001
Dyslipidemia 6.71 (5.03–8.96) <0.001 5.03 (3.61–7.02) <0.001
Female patients
BMI 1.09 (1.04–1.14) <0.001 1.02 (0.96–1.07) 0.553
HTN 5.94 (3.81–9.26) <0.001 3.71 (2.20–6.25) <0.001
DM 3.09 (2.23–4.30) <0.001 2.01 (1.23–3.28) 0.006
Dyslipidemia 10.37 (7.19–14.95) <0.001 8.15 (5.49–12.09) <0.001
HbA1c 1.34 (1.18–1.52) <0.001 1.03 (0.87–1.23) 0.726
Smoking 3.62 (1.54–8.52) 0.003 2.76 (0.98–7.80) 0.055

Non-parametric tests were performed for continuous variables that did not show normal distribution and are presented as median (25–75 percentile range).

Results are expressed as odds ratios (ORs) and 95% confidence intervals (CIs). Variables with p < 0.1 by univariate analysis were entered into the multivariate analysis model. HTN, hypertension; DM, diabetes mellitus; HbA1c, hemoglobin A1c, LDL, low-density lipoprotein; BMI, body mass index.