Table 2.
The frequencies of antibody positivity in all RPL patients and when grouping the patients according to plasma-MBL level, HLA-DRB1*03, or HLA-DRB1*07 phenotype, respectively.
| All RPL | Mannose-binding lectin plasma level | HLA-DRB1*03 | HLA-DRB1*07 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total | ≤500 µg/l | >500 µg/l | Pos | Neg | Pos | Neg | ||||
| AB | (N= 644) N, % |
(N= 237) N, % |
(N= 407) N, % |
P | (N= 134) N, % |
(N= 510) N, % |
P | (N= 126) N, % |
(N=518) N, % |
P |
| ANA | 82 12.7% |
35 14.8% |
47 11.6% |
0.24 | 22 16.4% |
60 11.8% |
0.15 | 18 14.3% |
64 12.4% |
0.56 |
| TPO | 86 13.4% |
36 15.2% |
50 12.3% |
0.30 | 18 13.4% |
68 13.3% |
0.98 | 14 11.1% |
72 13.9% |
0.41 |
| APL | 50 7.7% |
19 8.0% |
31 7.6% |
0.86 | 12 9.0% |
38 7.5% |
0.56 | 5 4.0% |
45 8.7% |
0.08 |
| 1 AB | 148 23.0% |
55 23.2% |
93 22.9% |
0.76 | 28 20.9% |
120 23.5% |
0.66 | 30 23.8% |
118 22.8% |
0.84 |
| ≥1 AB | 183 28.4% |
72 30.4% |
111 27.3% |
0.39 | 39 29.1% |
144 28.2% |
0.84 | 36 28.6% |
147 28.3% |
0.97 |
| ≥2 AB | 35 5.4% |
17 7.2% |
18 4.4% |
0.14 | 11 8.2% |
24 4.7% |
0.11 | 6 4.8% |
29 5.6% |
0.71 |
AB, antibody; Pos, positive; Neg, Negative; ANA, antinuclear antibody; TPO, thyroid-peroxidase; APL, antiphospholipid.