Table 3.
The frequency of carrying at least one of the HLA-DRB1 alleles in patients grouped according to presence or absence of at least one of the investigated autoantibody classes and low or normal plasma MBL levels.
| HLA-DRB1 phenotype | 0 AB | ≥1 AB | ||||
|---|---|---|---|---|---|---|
| MBL ≤500 µg/l Ntotal=165 N (%) |
MBL >500 µg/l Ntotal=296 N (%) |
P | MBL ≤500 µg/l Ntotal=72 N (%) |
MBL >500 µg/l Ntotal=111 N (%) |
P | |
| 01 | 31 (18.8) | 66 (22.3) | 0.38 | 13 (18.1) | 23 (20.7) | 0.66 |
| 03 | 35 (21.2) | 60 (20.3) | 0.81 | 22 (30.6) | 17 (15.3) | 0.01 |
| 04 | 53 (32.1) | 92 (31.1) | 0.82 | 24 (33.3) | 43 (38.7) | 0.46 |
| 07 | 31 (18.8) | 59 (19.9) | 0.77 | 12 (16.7) | 24 (21.6) | 0.41 |
| 08 | 14 (8.5) | 17 (5.7) | 0.26 | 8 (11.1) | 9 (8.1) | 0.49 |
| 09 | 5 (3.0) | 10 (3.4) | 1.0 | 1 (1.4) | 4 (3.6) | 0.65 |
| 10 | 3 (1.8) | 4 (1.4) | 0.71 | 1 (1.4) | 2 (1.0) | 1.0 |
| 11/12 | 32 (19.4) | 48 (16.2) | 0.39 | 17 (23.6) | 23 (20.7) | 0.54 |
| 13 | 49 (29.7) | 77 (26.0) | 0.40 | 15 (20.8) | 26 (23.4) | 0.68 |
| 14 | 7 (4.2) | 22 (7.4) | 0.18 | 7 (9.7) | 6 (5.4) | 0.27 |
| 15 | 46 (27.9) | 88 (29.7) | 0.68 | 14 (19.4) | 30 (27.3) | 0.24 |
| 16 | 2 (1.2) | 5 (1.7) | 1.0 | 3 (4.2) | 3 (2.7) | 0.68 |
AB, antibody; MBL, mannose binding lectin. The bold values denote statistically significant P-values.