Table 5.
The frequency of each of the three autoantibody classes in patients with or without the HLA-DRB1*03/low plasma MBL combination.
| HLA-DRB1 phenotype and p-MBL level combination | ||||||||
|---|---|---|---|---|---|---|---|---|
| AB | DRB1*03 pos Ntotal =134 |
DRB1*03 pos and MBL ≤500 µg/l Ntotal=57 |
DRB1*03 neg and/or MBL >500 µg/l Ntotal=587 |
OR (95% CI) |
p | |||
| B | % | N | % | N | % | |||
| ANA | 22 | 16.4 | 12 | 21.1 | 70 | 11.9 | 2.0 (1.0-3.9) |
0.05 |
| TPO | 18 | 13.4 | 11 | 19.3 | 75 | 12.8 | 1.7 (0.8-3.2) |
0.17 |
| APL | 12 | 9.0 | 6 | 10.5 | 44 | 7.5 | 1.5 (0.6-3.6) |
0.41 |
AB, antibody; OR, odds ratio; CI, confidence interval; ANA: antinuclear antibody; TPO, thyroid-peroxidase; APL, antiphospholipid; MBL, mannose-binding lectin; aTwo patients had missing ANA measurement and one had missing TPO measurement. The bold values denote statistically significant P-values.