Table 1.
Summary of cases with paraganglioma of the gallbladder.
| Case no. | Source year | Age (years)/sex | Clinical manifestation | Imaging characteristics | Size (cm) | Location | Associated findings | Hormone secretion | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Miller (9), 1972 |
67/M | Recurrent hematemesis | Duodenal ulcer next to scarred duodenal bulb | 3.0 | NM | Tumor bleeding cholecystoduodenal fistula |
NM | |
| 2 | Wolff (10), 1973 |
32/F 52/F 59/F |
Cholelithiasis Cholelithiasis Cholelithiasis |
NM NM NM |
NM NM NM |
Subserosal Subserosal Subserosal |
Chronic cholecystitis Chronic cholecystitis Chronic cholecystitis |
NM NM NM |
|
| 3 | Kawabata (11), 1999 |
51/M 55/M |
Hypochondralgia Epigastralgia |
Gallbladder stones Hepatobiliary lithiasis |
0.5 × 0.3 0.3 × 0.2 |
Subserosal Subserosal |
Liver dysfunction Chronic cholecystitis |
NM | |
| 4 | Hirano (12), 2000 |
58/F | Right hypochondrial pain | Lesion in the neck of gallbladder | 1.3 × 0.9 | Submucosal | None | No | |
| 5 | Cho et al. (13), 2001 |
45/F | Intermittent right upper quadrant pain | Fundal mass with diffusely thickened wall | 2.5 | NM | Tumor bleeding with chronic cholecystitis | No | |
| 6 | Mehra (5), 2005 |
36/M | None | Normal | 1.5 | Subserosal | Chronic cholecystitis | NM | |
| 7 | Sakuma (14), 2011 |
38/M | Hepatic hilus tumor | Heterogeneous mass and cholelithiasis | NM | Subserosal | Ectopic pheochromocytoma | NM | |
| 8 | İlhan Ece (15), 2015 |
57/F | Intermittent right upper quadrant pain | Gallbladder stones and a mass within the triangle of Calot | 1.8 | Subserosal | Chronic cholecystitis | NM | |
| 9 | Raha (16), 2018 |
NM | Right upper quadrant pain | Gallbladder stones | NM | Subserosal | Paraganglioma of the cystic duct | No | |
| 10 | Karel (17), 2019 |
36/M | Mild hypertension and tinnitus | A lesion with arterial enhancement adjacent to the gallbladder | 2.2 | NM | Elevated plasma dopamine level associated with SDHD mutation | Yes | |
| 11 | Furrukh (6), 2020 |
63/F | Recurrent biliary colic | Mildly dilated gallbladder | NM | Submucosal | Chronic cholecystitis | No | |
| 12 | Shukla (18), 2021 |
72/F | Discomfort in both ears accompanied by hearing loss | A lesion was seen in the neck of the gallbladder | 2.3 × 2.2 | NM | Familial paraganglioma syndromes | NM | |
| 13 | Present case | 48/F | Physical examination revealed a liver mass | A tumor with a rich blood supply in the middle lobe of the liver | 6.0 × 4.0 | Submucosal | Paraganglioma of the gallbladder |
No | |
*NM indicates not mentioned.