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. 2023 Jan 26;12:1031112. doi: 10.3389/fonc.2022.1031112

Table 1.

Summary of cases with paraganglioma of the gallbladder.

Case no. Source year Age (years)/sex Clinical manifestation Imaging characteristics Size (cm) Location Associated findings Hormone secretion
1 Miller (9),
1972
67/M Recurrent hematemesis Duodenal ulcer next to scarred duodenal bulb 3.0 NM Tumor bleeding
cholecystoduodenal fistula
NM
2 Wolff (10),
1973
32/F
52/F
59/F
Cholelithiasis
Cholelithiasis
Cholelithiasis
NM
NM
NM
NM
NM
NM
Subserosal
Subserosal
Subserosal
Chronic cholecystitis
Chronic cholecystitis
Chronic cholecystitis
NM
NM
NM
3 Kawabata (11),
1999
51/M
55/M
Hypochondralgia
Epigastralgia
Gallbladder stones
Hepatobiliary lithiasis
0.5 × 0.3
0.3 × 0.2
Subserosal
Subserosal
Liver dysfunction
Chronic cholecystitis
NM
4 Hirano (12),
2000
58/F Right hypochondrial pain Lesion in the neck of gallbladder 1.3 × 0.9 Submucosal None No
5 Cho et al. (13),
2001
45/F Intermittent right upper quadrant pain Fundal mass with diffusely thickened wall 2.5 NM Tumor bleeding with chronic cholecystitis No
6 Mehra (5),
2005
36/M None Normal 1.5 Subserosal Chronic cholecystitis NM
7 Sakuma (14),
2011
38/M Hepatic hilus tumor Heterogeneous mass and cholelithiasis NM Subserosal Ectopic pheochromocytoma NM
8 İlhan Ece (15),
2015
57/F Intermittent right upper quadrant pain Gallbladder stones and a mass within the triangle of Calot 1.8 Subserosal Chronic cholecystitis NM
9 Raha (16),
2018
NM Right upper quadrant pain Gallbladder stones NM Subserosal Paraganglioma of the cystic duct No
10 Karel (17),
2019
36/M Mild hypertension and tinnitus A lesion with arterial enhancement adjacent to the gallbladder 2.2 NM Elevated plasma dopamine level associated with SDHD mutation Yes
11 Furrukh (6),
2020
63/F Recurrent biliary colic Mildly dilated gallbladder NM Submucosal Chronic cholecystitis No
12 Shukla (18),
2021
72/F Discomfort in both ears accompanied by hearing loss A lesion was seen in the neck of the gallbladder 2.3 × 2.2 NM Familial paraganglioma syndromes NM
13 Present case 48/F Physical examination revealed a liver mass A tumor with a rich blood supply in the middle lobe of the liver 6.0 × 4.0 Submucosal Paraganglioma of the
gallbladder
No

*NM indicates not mentioned.