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CAIX expression in HB patient samples and normal liver. CAIX expression was restricted to bile duct cells in normal liver tissue (A, B). 9/21 HB tumor samples demonstrated intermediate (C, D) and 6/21 high CAIX immunoreactivity (E, F). CAIX expression localized to small clusters in the middle of viable HB tissue (arrow, C, D) or adjacent to necrotic areas (arrowhead, E, F). Scale bars: 50 µm (A) and 20 µm (B).
