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. 2023 Feb 9;13(8):5186–5196. doi: 10.1039/d2ra08016h

Optimizing the reaction conditions of catalytic one-pot reaction amines with aldehydesa.

graphic file with name d2ra08016h-u2.jpg
Entry Substrate Conv. (%) c Sel. (%) d Sel. (%)
1 graphic file with name d2ra08016h-u3.jpg >99 >99
2 graphic file with name d2ra08016h-u4.jpg >99 >99
3 graphic file with name d2ra08016h-u5.jpg >99 >99
4 graphic file with name d2ra08016h-u6.jpg >99 4 96
5 graphic file with name d2ra08016h-u7.jpg >99 >99
6 graphic file with name d2ra08016h-u8.jpg >99 >99
7 graphic file with name d2ra08016h-u9.jpg >99 >99
8 graphic file with name d2ra08016h-u10.jpg >99 >99
9 graphic file with name d2ra08016h-u11.jpg >99 >99
10 graphic file with name d2ra08016h-u12.jpg >99 >99
11 graphic file with name d2ra08016h-u13.jpg >99 >99
a

Reaction conditions: 25 °C, atmospheric pressure, 5 mg catalyst, 0.5 mmol aldehydes, 1 mmol amines, 3 mL EtOH, H2 balloon, reaction time: 1 h.