Table 3.
Relationship between CAD severity and various risk factors
| Variables | Multi-vessel coronary artery disease | ||
|---|---|---|---|
| OR(95%CI) | β | P-value | |
| Age | 1.033 (1.020–1.046) | 0.032 | < 0.001 |
| Sex | |||
| Male | Reference | ||
| Female | 1.360 (0.986–1.875) | 0.307 | 0.061 |
| Glucose metabolism state | |||
| NGR | Reference | ||
| Pre-DM | 0.935 (0.663–1.318) | − 0.067 | 0.702 |
| DM | 2.151 (1.493–3.098) | 0.766 | < 0.001 |
| Smoking | |||
| NO | Reference | ||
| YES | 0.766 (0.578–1.015) | − 0.267 | 0.063 |
| Drinking | |||
| NO | Reference | ||
| YES | 0.832 (0.559–1.239) | − 0.183 | 0.366 |
| Hypertension | |||
| NO | Reference | ||
| YES | 1.388 (1.046–1.840) | 0.328 | 0.023 |
| BMI | 1.015 (0.971–1.061) | 0.015 | 0.502 |
| HbA1c | 1.293 (1.148–1.456) | 0.257 | < 0.001 |
| Glucose | 1.180 (1.119–1.245) | 0.166 | < 0.001 |
| TC | 1.005 (0.897–1.126) | 0.005 | 0.936 |
| TG | 1.009 (0.884–1.151) | 0.009 | 0.896 |
| HDL-C | 0.568 (0.344–0.938) | − 0.566 | 0.027 |
| LDL-C | 0.996 (0.868–1.144) | − 0.004 | 0.960 |
| UA | 1.002 (0.999–1.006) | 0.002 | 0.117 |
| Cr | 0.999 (0.998–1.001) | < − 0.001 | 0.972 |
| BNP | 1.000 (1.000–1.001) | < 0.001 | 0.009 |
| D-dimer | 1.000 (0.999–1.001) | < 0.001 | 0.763 |
| CRP | 1.020 (0.994–1.047) | 0.020 | 0.135 |
| LAD | 1.032 (1.000–1.064) | 0.031 | 0.048 |
| LVDd | 1.013 (0.988–1.039) | 0.013 | 0.319 |
| LVDs | 1.021 (0.999–1.043) | 0.021 | 0.053 |
| IVS | 1.068 (0.962–1.187) | 0.066 | 0.216 |
| LVPW | 1.021 (0.909–1.146) | 0.020 | 0.731 |
| LVEF | 0.999 (0.999–1.000) | < − 0.001 | 0.053 |
| SHR | 4.590 (2.598–8.111) | 1.524 | < 0.001 |
OR odds ratios, CI confidence interval, β regression coefficient, NGR normal glucose regulation, Pre-DM pre-diabetes mellitus, DM diabetes mellitus, HbA1c glycated hemoglobin A1c, BMI body mass index, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, UA uric acid, Cr creatinine, LAD left atrial diameter, LVDd left ventricular end diastolic diameter, LVDs left ventricular systolic diameter, IVS interventricular septal thickness, LVPW left posterior wall thickness, LVEF left ventricular ejection fraction, BNP B-type natriuretic peptide, CRP C-reactive protein, SHR stress hyperglycemia ratio