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. 2023 Feb 9;12:8. doi: 10.1186/s40249-023-01059-2

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Kinetics of urinary biomarkers during and after CM (surviving children at D0, D3, D30). Levels of creatinine, 15-F2t-isoprostane (Isop), PGE2 metabolites (PGEM), LTB4, LXA4, reduced (GSH) and oxidized (GSSG) glutathione were measured in the urine of children at inclusion (D0) and 3 (D3) and 30 days (D30) after inclusion by enzyme immunoassays kits. Two-by-two comparisons (D0 to D3 and D3 to D30) were carried out by the Wilcoxon matched-pairs signed rank test. Values are all in pg/ml. A Creatinine, 15-F2t-isoprostane, PGEM, and LTB4 levels. B LXA4, GSH, GSSG and GSH/GSSG ratio levels. *P < 0.05, ^**P < 0.005, ***P < 0.0005