Table 4.
Immunological factors measured in urine associated with death among cerebral malaria infant, multivariate logistic regression, n = 70
| Factors | Survival, % (n) | Death, % (n) | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | aOR (95% CI) | P-value | ||||
| Urinary creatinine (mg/ml) | < 0.60 | 87.1 (27) | 12.9 (4) | 1 | |||
| ≥ 0.60 | 70.9 (22) | 29.0 (9) | 2.76 (0.75–10.2) | 0.13 | |||
| LXA4/creatinine (ng/mg) | < 0.79 | 68.9 (20) | 32.3 (10) | 1 | |||
| ≥ 0.79 | 87.1 (27) | 12.9 (4) | 0.31 (0.08–1.13) | 0.08 | |||
| IsoP/creatinine (ng/mg) | < 4.63 | 68.7 (22) | 31.3 (10) | 1 | |||
| ≥ 4.63 | 90.0 (27) | 10.0 (3) | 0.24 (0.06–0.99) | 0.05 | |||
| PGEM/creatinine (ng/mg) | < 0.43 | 67.7 (21) | 32.3 (10) | 1 | 1 | ||
| ≥ 0.43 | 89.7 (26) | 10.3 (3) | 0.24 (0.06–0.99) | 0.05 | 0.31 (0.06–1.49) | 0.14 | |
OR Odd ratio; aOR Adjsuted odd ratio; adjusted for Blantyre score, presence of icterus, hypoglycaemia, and blood creatinine; CI Confidence interval