TABLE 3.
TGFB1 and TGFBI are the top markers for microglia/macrophage in the brain.
| Cluster | Annotation | Gene | p_value | avg_diff | pct.1 | pct.2 |
|---|---|---|---|---|---|---|
| Adult-Cerebellum1_Cluster16 | Macrophage | TGFBI | 5.82E-63 | 1.8518 | 0.367 | 0.011 |
| Fetal-Brain_Zhong_Cluster3 | Microglia | TGFB1 | 1.46E-48 | 1.1991 | 0.284 | 0.013 |
| Fetal-Brain4_Cluster10 | Macrophage | TGFBI | 1.33E-15 | 0.8792 | 0.158 | 0.005 |
| Fetal-Brain5_Cluster11 | M2 macrophage | TGFBI | 4.94E-30 | 1.6913 | 0.348 | 0.016 |
| Fetal-Brain5_Cluster6 | Fibroblast | TGFBI | 6.48E-91 | 1.5493 | 0.254 | 0.011 |
Note: Single-cell differential gene expression analysis for four brain tissues was performed on the Human Cell Landscape website; p < 0.05 was considered statistically significant.