Skip to main content
. 2023 Jan 16;19(3):967–980. doi: 10.7150/ijbs.76407

Figure 3.

Figure 3

BC002811 regulates tumor growth and metastasis in vivo. (A) Representative images of tumor xenografts formed in nude mice following injection of HGC-27 and AGS cells viewed with an IVIS® Lumina II Imaging System. The luciferase signals were imaged in mice bearing tumors from BC002811 stable knockdown (green arrow) or control (red arrow) HGC-27 cells, and BC002811 stable overexpressing (red arrow) or control (green arrow) AGS cells. (B) Statistical analysis of the luciferase signals in mouse xenograft models. (C) Images and (D) weights of tumor xenografts from nude mice in each group. (E) Images of mice in each group after tail vein injections of HGC-27 or AGS cells. (F) The luciferase signals of mice in each group after tail vein injections. (G) Hematoxylin and eosin-stained (H&E) images of lungs harvested from nude mice in each treatment group. Scale bars, 2 mm (10× images) and 1 mm (20× images). (H) Number of lung metastasis nodules. Data expressed as mean±SD. *P < 0.05, **P <0.01.