Table 7.
Cox regression analysis evaluating the association of drugs with mortality among patients with severe disease.
| Variable | Univariate |
Multivariate |
||
|---|---|---|---|---|
| HR | p-value | Adjusted HR | p-value | |
| Sex (male) | 1.17 (0.70–1.95) | 0.550 | 0.86 (0.51–1.48) | 0.592 |
| Age (≥60 years) | 0.94 (0.58–1.54) | 0.810 | 1.06 (0.63–1.78) | 0.818 |
| Comorbidity present (any) | 1.00 (0.57–1.74) | 0.994 | 0.94 (0.52–1.69) | 0.827 |
| Drugs | ||||
| Steroids | 0.36 (0.21–0.59) | <0.001∗ | 1.62 (0.62–4.28) | 0.328 |
| Antibiotics | 0.19 (0.12–0.33) | <0.001∗ | 0.29 (0.13–0.65) | 0.003∗ |
| Anticoagulants | 0.21 (0.12–0.36) | <0.001∗ | 0.43 (0.17–1.12) | 0.080 |
| Favipiravir | 0.29 (0.13–0.63) | 0.002∗ | 0.40 (0.17–0.98) | 0.044∗ |
| Remdesivir | 0.45 (0.25–0.82) | 0.009∗ | 0.76 (0.33–1.77) | 0.523 |
COVID-19, coronavirus disease 2019; HR, hazard ratio; ∗, statistically significant (p-value <0.05).