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. 2022 Nov 11;36(11):431–442. doi: 10.1089/apc.2022.0111

Table 6.

Preferences for Pre-Exposure Prophylaxis Modalities Across Classes

  Class 1: Shared decision-making
Class 2: Provider-led decision-making
Class 3: Patient-driven decision-making
OR aOR OR aOR Class 1 versus 2 (p of interaction term in adjusted models) OR aOR Class 1 versus 3 (p of interaction term in adjusted models) Class 2 versus 3 (p of interaction term in adjusted models)
Daily oral PrEP REF REF REF REF REF REF REF REF REF
bnAb 0.45*** 0.41*** 0.33*** 0.29*** 0.043* 0.36*** 0.33** 0.14 0.44
Rectal douche 0.28*** 0.22*** 0.19*** 0.14*** 0.013* 0.25*** 0.19*** 0.39 0.07
PrEP implant 0.67*** 0.67*** 0.32*** 0.31*** <0.0001*** 0.46*** 0.46* 0.01* 0.02*
Injectable PrEP 1.00 1.05 0.64*** 0.66* 0.008** 0.83 0.86 0.20 0.10
Event-driven 1.00 0.96 0.67** 0.64** 0.015* 0.94 0.89 0.63 0.04*

Omnibus test for overall differences in preferences across classes: Wald χ2(df=10) = 23.34, p < 0.01 (unadjusted model); Wald χ2(df=10) = 22.17, p = 0.01 (adjusted models).

*

p < 0.05; **p < 0.01; ***p < 0.001.

bnAb, broadly neutralizing antibodies.

Adjusted models control for age, race/ethnicity, and sexual identity.