Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The main role of matrix metalloproteinases (MMPs) in colitis and colitis-associated cancers (CAC). MMPs are involved in pathological processes of colitis and CAC, including cell growth and division, angiogenesis and migration, ECM remodeling and invasion, as well as inflammation and immune response. ROS, reactive oxygen species; ITF, intestinal trefoil factor; Sp1, specificity protein 1; ECM, extracellular matrix.
