Table 3.

Top 30 False-Discovery Rate (FDR)-Significant Findings from the Pathway Analyses.

Gene Set	Description	Meta-Analysis Ratio	European-Americans Ratio	African-Americans Ratio	Hispanic-Americans Ratio	Asian-Americans Ratio
hsa00604	Glycosphingolipid biosynthesis	4.98
hsa04710	Circadian rhythm	3.37
hsa04520	Adherens junction	3.32
hsa04924	Renin secretion	3.22	2.88		2.75
hsa04540	Gap junction	3.06	2.66
hsa04724	Glutamatergic synapse	3.01	2.33	2.67	2.99
hsa04921	Oxytocin signaling	2.95		2.31	2.56	2.25
hsa05412	Arrhthmogenic righ ventricular cardiomyopathy	2.90	2.82	2.75	3.16	3.09
hsa04927	Cortisol synthesis and secretion	2.80	3.42	2.86
hsa04713	Circadian entrainment	2.80	2.60	2.22	2.71
hsa04925	Aldosterone synthesis and secretion	2.65	2.44	2.70	2.37
hsa04360	Axon guidance	2.56	1.96	2.00
hsa05414	Dilated cardiomyopathy	2.49		2.37	2.53	2.66
hsa04270	Vascular smooth muscle contraction	2.47	2.32	2.65
hsa04020	Calcium signaling	2.45	2.22	2.08	2.13
hsa04070	Phosphatidylinositol signaling	2.41	2.37	2.46
hsa04912	GnRH signaling	2.41
hsa04725	Cholinergic synapse	2.40	2.23	2.99
hsa04072	Phospholipase D signaling	2.35	2.46	2.40	2.22	2.34
hsa05410	Hypertrophic cardiomyopathy	2.34			2.74	2.68
hsa04911	Insulin secretion	2.28
hsa04750	Inflammation/transient receptor potential channels	2.26		2.31
hsa04022	Cyclic guanosine monophosphate-protein kinase G signaling	2.11		2.62
hsa04024	Cyclic adenosine monophosphate signaling	2.10	2.36	1.91
hsa04371	Apelin signaling pathway	2.07
hsa04728	Dopaminergic synapse	2.05
hsa04015	Ras-associated protein-1 signaling	2.03	1.82	2.15	1.89
hsa04261	Adrenergic signaling cardiomyocytes	1.97	2.17			2.49
hsa04514	Cell adhesion molecules	1.97		2.01	2.14	2.26
hsa04934	Cushing syndrome	1.94	2.03

Notes: All values shown are significant at FDR < 0.05.