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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Nat Genet. 2022 Sep 29;54(10):1479–1492. doi: 10.1038/s41588-022-01187-9

Extended Data Fig. 2. Standardized effect sizes of immune and brain cell type programs.

Extended Data Fig. 2.

Standardized effect size (τ*) (dot size) and significance (−log10(P-value), dot color) of the heritability enrichment of immune (a,b) or brain (c) cell type programs (columns) for blood cell traits (a), immune disease traits (b), or neurological/psychological related traits (c), based on SNP annotations generated with the Roadmap∪ABC-immune (a,b) or Roadmap∪ABC-brain (c) enhancer-gene linking strategy. Numerical results are reported in Supplementary Data 1. Details for all traits analyzed are in Supplementary Table 2.