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. 2023 Feb 9;14:23. doi: 10.1186/s13287-022-03234-y

Table 4.

Changes of scales from baseline to month 24 in the treatment group

Baseline 1 M 3 M 6 M 24 M P value
FMFS 24.00 ± 15.85 28.42 ± 16.57 29.33 ± 15.68 31.54 ± 17.93 36.56 ± 17.86* .010*
SS 26.68 ± 18.65 30.58 ± 18.54 34.17 ± 17.40 32.82 ± 17.82* 39.00 ± 16.73** .000**
LAS 29.36 ± 21.00 32.12 ± 20.65 33.46 ± 18.63 33.32 ± 19.87 39.23 ± 19.27 .205
EAS 29.29 ± 21.41 33.31 ± 21.21 36.92 ± 19.86* 33.86 ± 20.08* 39.14 ± 19.36* .003*
GMFM-88-A (Lying and Rolling) 45.36 ± 11.53 47.77 ± 9.98 47.33 ± 10.33 48.29 ± 8.82 47.82 ± 9.91 .084
GMFM-88-B (Sitting) 39.29 ± 20.57 49.85 ± 19.27 52.58 ± 16.05 50.29 ± 19.08 53.36 ± 16.82 .040*
GMFM-88-C (Crawling and Kneeling) 19.79 ± 14.29 28.46 ± 14.56 31.33 ± 12.15 27.29 ± 13.76 35.18 ± 12.17 .014*
GMFM-88-D (Standing) 15.86 ± 10.33 22.85 ± 11.51* 25.92 ± 9.42* 23.14 ± 11.79 25.36 ± 10.39** .001**
GMFM-88-E (Walking, Running and Jumping) 14.29 ± 13.60 21.77 ± 15.24** 25.75 ± 17.13** 26.07 ± 19.21** 31.18 ± 18.79** .000**
GMFM-88-TOTAL 52.41 ± 24.44 66.66 ± 25.02 71.45 ± 22.29* 67.95 ± 24.72* 74.95 ± 23.84* .001**
ADL 34.54 ± 20.90 45.85 ± 24.34** 52.08 ± 24.38** 50.82 ± 27.00** 61.68 ± 26.16** .000**

Data are summarized as the mean ± SD (standard deviation). 1 M: 1 month after treatment; 3 M: 3 months after treatment; 6 M: 6 months after treatment; 24 M: 24 months after treatment; GMFM: Gross Motor Function Measure; ADL: Activity of Daily Living; FMFS: Fine Motor Function Scale; SS: Sociability Scale; LAS: Life Adaptability Scale; EAS: Expressive Ability Scale

*P < 0.05; **P < 0.01